The bullous form of urticaria is so uncommon that several dermatologic textbooks in recent years only mention it by name. Hebra4 stated that the affection developed chiefly on the surface of preexisting wheals, rather than on the surrounding erythematous areola. He differentiated it from pemphigus and bullous erysipelas. Frieboes2 observed vesiculating urticaria most frequently on the palms and soles of children and distinguished it from bullous congenital syphilis and scabies. Flandin1 labeled the condition Kaposi's vesicular or bullous urticaria. He wrote that it complicated ordinary urticaria, but that the bullous lesions, which rapidly underwent desiccation and crust formation, were not as numerous as the remainder of urticarial lesions. In his opinion, this condition was most frequently confused with dermatitis herpetiformis and pemphigus. Van der Meiren and Achten,6 reporting three cases of bullous urticaria, clinically and histologically, thought they were able to demonstrate multilocular intraepidermal
WINER LH. Bullous Urticaria. AMA Arch Derm. 1957;76(4):471–475. doi:10.1001/archderm.1957.01550220079016
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