Received for publication May 21, 1957.
There are a large number of agents that are used for local anesthesia by injection. Most of them I have found have one or more objections. The most commonly used ones are procaine hydrochloride, lidocaine (Xylocaine), and hexylcaine (Cyclaine). All are used in strengths of 1% to 2%. Some men have used these anesthetics with epinephrine hydrochloride added as a vasoconstrictor for hemostasis. Epinephrine has some undesirable side-effects, however, and because of these it is not frequently used.
I have used the three anesthetics mentioned above and have found objections to all. Subcutaneous injections of procaine do not give immediate anesthesia, and I have been frequently forced to wait up to five minutes for a complete anesthesia. Lidocaine and hexylcaine are excellent agents, but cause discomfort and pain to the patient when injected. Patients complain quite frequently of burning and
WORTZEL MH. A Superior Local Anesthetic. AMA Arch Derm. 1957;76(4):500. doi:10.1001/archderm.1957.01550220108019
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