[Skip to Navigation]
November 1957

The Treatment of Pityriasis Rosea with Convalescent Plasma, Gamma Globulin, and Pooled Plasma

Author Affiliations

Santa Cruz, Calif.; Ann Arbor, Mich.

From the Department of Dermatology and Syphilology, University Hospital, University of Michigan Medical School.

AMA Arch Derm. 1957;76(5):659-662. doi:10.1001/archderm.1957.01550230125018

Pityriasis rosea is usually considered a completely harmless, though occasionally annoying, dermatologic entity. The standard textbooks currently in use1-4 concur in this. At times this disease becomes both annoying and embarrassing to the patient. In 1940, Niles and Klumpp5 were the first, to our knowledge, to attempt the treatment of pityriasis rosea with convalescent plasma. In March, 1956, it was decided to further investigate their results during the usual spring rise in the incidence of pityriasis rosea at the University of Michigan campus and the University of Michigan Hospital.

Many excellent reviews of the literature have been published.5-7 For this reason, only the aspects pertinent to our study will be discussed in this paper.

Niles and Klumpp5 and many others feel that there is at least suggestive evidence that this entity is probably due to a filtrable virus. The seasonal and epidemic nature of its