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February 1958

Sebaceous Carcinoma: Report of Case Developing in Area of Radiodermatitis

Author Affiliations


From the Departments of Pathology, Harvard Medical School and Boston Veterans' Administration Hospital.

AMA Arch Derm. 1958;77(2):195-200. doi:10.1001/archderm.1958.01560020047005

The occurrence of skin cancer resulting from therapeutic and occupational irradiation with x-rays has been extensively documented clinically and amply confirmed experimentally since 1902, seven years after Roentgen's discovery.1,2 It has been reported anywhere from 2 to more than 30 years after ionizing radiation,3 and according to Willis the malignancy is "always of the squamous-cell type."4 However, basalcell carcinomas have also been described,5 and the case herein reported suggests that sebaceous carcinoma may also be included in the list of radiation-induced malignancies. This apparently is the first reported case illustrating the possibility that sebaceous carcinoma can arise as the result of radiation injury.

Report of Case

A 30-year-old white oil-delivery man was admitted to the Boston Veterans' Administration Hospital on Jan. 22, 1957, because of x-ray dermatitis of the face, neck, and upper chest.

While in the Navy

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