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March 1958


AMA Arch Derm. 1958;77(3):347-350. doi:10.1001/archderm.1958.01560030093023

Reticuloendotheliosis (Letterer-Siwe Disease) in Sisters. Presented by Dr. John W. Dougherty.

A 5-month-old Negro female infant is presented from New York Hospital with an eruption, which has been present since birth, of the trunk and head. She was born to a 33-year-old septigravida sextipara who had had one abortion and who was considered to have had inactive pulmonary tuberculosis for four to five years prior to 1957. During pregnancy with the patient gastric samples were taken in the fifth month of pregnancy and were said to be positive, and so the mother was hospitalized in October in Triboro Hospital, where she was given isoniazid and p-aminosalicylic acid. No known antituberculosis therapy had been given prior to that time.

The patient was born on Dec. 11, 1956, while the mother was hospitalized. Delivery was uncomplicated, and the birth weight was 8 lb., 4 oz. The

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