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May 1958

Dynamics of Autosensitization Dermatitis: A Clinical and Microscopic Concept of Autoeczematization

Author Affiliations

New York

From The Department of Dermatology, St. Luke's Hospital.

AMA Arch Derm. 1958;77(5):495-502. doi:10.1001/archderm.1958.01560050001001

Autoeczematization1,2 is the process by which a widespread dermatitis may complicate several types of localized eczema. Generalized autogenous eczema describes the disseminate disorder. This report deals with the clinical history, course, and development of the syndrome and with the microscopic picture of various types of lesions to be found in the diffuse and often generalized eruption. Relationships between generalized autogenous eczema, disseminate and circumscribed neurodermatitis, nummular eczema, and exudative discoid and lichenoid chronic dermatosis are discussed.

Clinical Material

Sixty persons, thirty-three women and twenty-seven men, who developed generalized autogenous eczema were studied. The average age was 47.7 years; the youngest was 1 year, and the oldest, 80. Fifty-seven were of Caucasian origin, and three were Negro. Thirty-six patients either recalled eczema as a child or had hay fever or a history of allergy in the family. In seven, the history of an allergic background was

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