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June 1958


Author Affiliations

President; Secretary; Recorder Nov. 13, 1957 Ann Arbor, Mich.

AMA Arch Derm. 1958;77(6):750-751. doi:10.1001/archderm.1958.01560060116028

Periadenitis Mucosa Necrotica Recurrens. Presented by the Staff of the University Hospital, Ann Arbor, Mich.

The patient, a 36-year-old white woman, has had crateriform ulcerations of the buccal mucosa, palate, tongue, floor of the mouth, and lips since May, 1954.

A tender submaxillary lymph node is readily palpated.

Microscopic examination revealed "a small ulcer, fibrinous purulent exudate. Beneath this is granulation tissue infiltrated by various types of inflammatory cells. The degree of inflammation is more pronounced than is usually seen in recurrent aphthous stomatitis."

Steroid therapy and smallpox vaccine inoculations have proved ineffective.


Dr. James R. Rogin: I should like to give a progress report upon a patient I referred recently to the Dermatology Staff of the University Hospital in Ann Arbor, Mich. This was a white man, aged 44, who had had recurrent attacks of periadenitis (or extremely severe aphthous ulcers)

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