Darier's Disease. Presented by Dr. Clete S. Dorsey.
The patient is a 57-year-old white woman, born in America, who first noticed a scattering of discrete warty growths in both palms at the age of 12. Gradually, over a period of the next 30 years, discrete flesh-colored flat warty growths appeared elsewhere on her body, especially in the temple areas and the midline areas of her face and back. Until 10 years ago the condition was rather benign. The warty growths were flat and few in number, and, being flesh-colored, were easily covered with make-up. For the past 10 years, however, she has had constant medical attention because of other illnesses (bronchiectasis, emphysema, and chronic cardiac decompensation). As her health has failed, her skin condition has become worse. When she was first seen at the Good Hope Clinic, in August, 1955, her dermatosis involved the entire face, the neck, the upper chest and back, and the lower legs. On the upper part of her body, the lesions, although numerous, were for the most part discrete or in small groups.
Edward L. Murphy, Laurence J. Underwood, Eliot Wolk. THE METROPOLITAN DERMATOLOGICAL SOCIETY OF LOS ANGELES. AMA Arch Derm. 1958;77(6):758–761. doi:10.1001/archderm.1958.01560060124030