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July 1958

Pemphigus Vulgaris with Lesions of the Rectal Mucosa

Author Affiliations

San Francisco
From the Departments of Dermatology and Proctology, Mount Zion Hospital.

AMA Arch Derm. 1958;78(1):36-38. doi:10.1001/archderm.1958.01560070038005

It is the purpose of this paper to report a case of pemphigus vulgaris with rectal lesions. Wiener1 mentions in his text that specific lesions for pemphigus occasionally occur in the esophagus and rectum. However, we have been unable to uncover any cases similar to ours in the literature.

Report of a Case

A 48-year-old Jewish woman was first seen on an ambulatory basis on March 19, 1957, complaining of "painful raw areas" in the mouth. Examination revealed tender erythematous friable lesions with superficial denudation involving the lips, tongue, gums, palate, buccal mucosa, and, to a lesser extent, the pharynx and nasal mucous membranes. The ulcerations were most marked on the tongue, where a scalloped appearance of the edges was noted. The oral and nasal lesions were treated with hydrocortisone sprayed locally. Elixer of diphenhydramine (Benadryl) was used as a mouthwash before meals to reduce the

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