Granular-cell myoblastoma is a tumor which is rarely encountered in the skin. Of the reported cases, 33% have occurred in the tongue; only about 20% of these tumors have been found in the skin.1 This tumor has, however, been observed in various organs, including the external auditory meatus, the bronchi, the common bile duct,2 the maxilla, the parotid gland, the larynx, the orbit, the heart, the esophagus, the bladder, the urethra perineum, the anal region, and the ovary. Characteristically, it is a slowly growing, nondistinctive, sessile or pendunculated asymptomatic nodule which is usually solitary and which may eventually ulcerate. Paroxysmal pain has been a symptom in some patients. Multiple lesions are the exception rather than the rule. Malignant alteration with metastases may occur on rare occasions.3 It is difficult to classify malignant granular-cell myoblastoma. There are some who feel that it is malignant de
REBELLO DJA. Multiple Large Tumors of Granular-Cell Myoblastomata of the Skin: Report of a Case. AMA Arch Derm. 1958;78(1):85–88. doi:10.1001/archderm.1958.01560070089011
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