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September 1958

Mucinous Metaplasia in Normal Apocrine Glands

Author Affiliations

Rochester, Minn.

AMA Arch Derm. 1958;78(3):309-313. doi:10.1001/archderm.1958.01560090021005

The apocrine glands are specialized structures which normally produce a whitish fluid containing carbohydrate and protein. This fluid is said to be produced by the ejection of part of the cellular protoplasm of the secretory cells into the lumen of the glands. The material in the fluid forms a solid white mass when it dries at the surface. It has been assumed usually that this is a constant product, as no variations in its content or manner of production have been documented. The attempts to correlate function of the apocrine glands with various cycles of the body have been summarized by Montagna.1 He showed that no specific correlation existed between the menstrual cycle and the activity of the glands.

One of us (R. K. W.) and associates2,3 have described a Schiff-reactive, diastaseresistant, mucin-positive, nonmetachromatic material in the apocrine glands in Fox-Fordyce disease.

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