Pyoderma Gangrenosum: Probable Ulcerative Colitis; Pregnancy (Four Months). Presented by Dr. Donald M. Pillsbury and (by invitation) Dr. L. D. Aaronson.
A white woman aged 25, in moderate distress, complaining of pain in her right leg, presented on the extensor aspects of her elbows and on her buttocks numerous raised, firm, brownish lesions. On the left thigh was a large, circumscribed area of dermatitis measuring 14 cm. in diameter. This area consisted of an inner and an outer zone of granulation tissue separated from each other by a depressed zone 0.5 cm. in width containing purulent material. On the right lower leg was an extensive area of ulceration extending from the lateral aspect of the right ankle and continuing upwards, involving the lower half of the right leg. Distally there appeared to be granulation tissue and new skin. Proximally was a necrotizing border of skin which was grossly