Follicular hyperkeratosis is a feature of many diseases. Although its nature and pathogenesis have been attributed to diverse multiple and correlated factors, it still constitutes one of the most perplexing and controversial problems in dermatology. This is particularly true of those resulting in generalized cicatricial follicular atrophy with permanent alopecia. Nor is this divergence of opinion limited to the cause of the process; it includes the problem of terminology.
In the European literature, mention is made of follicular hyperkeratoses associated with cicatricial alopecia but few cases have been reported.
In the American literature, except for Graham-Little's disease (lichen planopilaris), consisting of the triad of lichen planus, acuminate follicular lesions, and alopecia, there is no mention of a condition corresponding to that described in the report which follows.
Report of a Case
A 69-year-old Italian woman consulted us for the first time in November, 1949, complaining of
REISS F, REISCH M, BUNCKE CM. Keratodermatitis Follicularis Decalvans. AMA Arch Derm. 1958;78(5):619–624. doi:10.1001/archderm.1958.01560110065009
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