An interesting clinical picture characterized by slowly extending serpiginous and polycyclic lesions with raised edges, hyperkeratosis of the flexures, and hyperhidrosis of the palms, present from birth, in a woman aged 23, was first described by Comel,1 in 1949. The back, abdomen, and proximal parts of the extremities were mainly involved; the condition became more pronounced at puberty, but there were subsequently some remissions. Comel suggested the term "ichthyosis linearis circumflexa."
In a review of the literature we were able to find only one further case report under this diagnosis. Frank's2 patient (1956), a man, showed almost identical clinical features. The condition had appeared within the first three months of life and had persisted.
We believe that the cases presented by Miescher,3 in 1954,
DANILO V. STEVANOVIC, RADOSLAV L. PAVIC. Dyskeratosis Ichthyosiformis Congenita MigransA Variant of Congenital Ichthyosiform Erythroderma. AMA Arch Derm. 1958;78(5):625–629. doi:10.1001/archderm.1958.01560110071010