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January 1959

Fluorescent Material in Scales, Nails, and Hair

AMA Arch Derm. 1959;79(1):96-98. doi:10.1001/archderm.1959.01560130098011

The ease with which hot water will extract fluorescent material from fluorescent hairs infected with Microsporum species1 has led to efforts at chemical identification of the substance. Felsher2 found it to behave as a fluorescent indicator substance. Robinson, Figge, and Bereston3 found it to be readily water-soluble and not soluble in most fat solvents. Their spectrographic analysis led them to believe the fluorescent material to be a small peptide-like molecule. Wolf,4 on the basis of spectrophotometric examinations, believes it to be a pteridine, although this has been questioned.5

Chattaway and Barlow6 were able to extract a fluorescent material from the hair of uninfected children, which gave a chromatogram different from that obtained from infected hair. Rebell, Mahvi, and Lamb7 were able to extract fluorescent materials from albino rat hair, which is normally fluorescent, but not from non-fluorescent hair of

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