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February 1959


Author Affiliations

Senior Specialist (Dermatology) General Hospital Lagos, Nigeria, West Africa

AMA Arch Derm. 1959;79(2):247. doi:10.1001/archderm.1959.01560140109017

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To the Editor:—I was most interested to read in the A. M. A. Archives of Dermatology 78:186, 1958, the article on larva currens.

Recently, I have tried treating larva migrans with Trafuril applied locally. I find it an effective remedy, and the results are sometimes dramatic. In other cases, however, it does not work, and I wondered if these were, in fact, cases of Strongyloides infection.

Trafuril (CIBA) is tetrahydro-furfuryl nicotinic acid ester, which is exhibited as a 5% rubefacient cream and is normally used to relieve muscular rheumatism, lumbago, etc. It may perhaps kill the larvae directly or alternatively sweep them away in the resulting hyperemia.

I feel this drug is worthy of further trial in creeping eruptions, as in my experience it is at least as good as freezing with ethyl chloride and considerably easier to apply.

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