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February 1959


AMA Arch Derm. 1959;79(2):251-257. doi:10.1001/archderm.1959.01560140113019

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Trichophyton Rubrum Infection of the Nails. Presented by Dr. Maurice J. Costello.

A woman aged 30 has had a Trichophyton rubrum infection of the toenails and fingernails for the past six years.

Treatment has consisted of the usual antifungal agents, including Verdefam, and surgical removal of the nails, followed by daily application of Isodine, with recurrence. Numerous antifungal agents have been used conscientiously without avail.

The patient saw a member of this society in consultation and since then has been applying pumice stone and double-strength Whitfield's ointment, without improvement; in fact, the infection has spread to the adjoining fingernails. The patient is presented for suggestions as to therapy.


Dr. Carl T. Nelson: These cases are extraordinarily difficult to cure and I have concluded that it is not so much the medication applied to kill the fungus that deserves study as it is the factors in the

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