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April 1959

Alopecia Mucinosa

Author Affiliations

(MC); (MC), U. S. Army; Washington, D. C.

AMA Arch Derm. 1959;79(4):395-406. doi:10.1001/archderm.1959.01560160013003

Alopecia mucinosa is a dermatosis recently described by Pinkus.1 Clinically it appears as single or multiple, slightly erythematous, raised plaques, associated with loss of hair in the sites involved. Pathologically, the changes are in the pilosebaceous apparatus; they are easily recognized and diagnosed.

After Dr. Pinkus presented his paper at the International Congress of Dermatology at Stockholm,2 Dr. Szodoray, of Budapest, said he had published a similar case with Lehner, in 1939, and also referred to a case published by Kreibich, in 1926. Kreibich3 described a generalized patchy eruption in a 20-year-old white youth, under the title "Mucin in a Skin Disease." The distinctive histopathological feature was the presence of cystic spaces and mucin within the pilosebaceous follicle. There was a perifollicular infiltrate with numerous lymphocytes and occasionally some mucinous material. He believed that the mucinous change preceded or possibly occurred at