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Clinical Notes, New Instruments and Techniques
April 1959

Lymphosarcoma with Involvement of the Skin

Author Affiliations

Fort Howard, Md.

AMA Arch Derm. 1959;79(4):480-481. doi:10.1001/archderm.1959.01560160098014

Massive involvement of the skin by a lymphoma occurs infrequently. The following patient is reported because of this interesting manifestation of the disease.

Report of a Case

A 68-year-old white man was admitted to the hospital on July 30, 1956, with a massive lesion of the face of three weeks' duration and dysphagia of one week's duration. An unknown new growth had been excised from the lower lip about eight years previously. A similar tumor was removed from the same region about four years previously. About two months before admission, a small lesion appeared on the right cheek. The patient was admitted to another hospital, where a biopsy revealed Hodgkin's disease. After a course of mechlorethamine hydrochloride (nitrogen mustard) was given intravenously, he was discharged. Rapid growth of the neoplasm followed.

The patient was pale, emaciated, cachetic, and alert. A large nodular lesion covered the right side

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