The keratotic skin lesions of keratosis blennorrhagica, which usually follow gonorrheal urethritis and polyarthritis, have been treated with many drugs, but none has found universal approval. In recent years the antibiotics and the corticosteroid hormones have been used with varying success, ranging from complete cure to little or no effect whatsoever.
It is difficult to evaluate the true benefit of therapeutic agents in keratosis blennorrhagica because (1) the condition is usually self-limited and (2) the disorder is encountered too infrequently for any investigator to have an adequate number of control cases.
The purpose of this paper is to review some of the literature on the treatment of keratosis blennorrhagica and to report our experience with the use of the antibiotics and corticosteroid hormones.
ALBERT J, CRONE RI. Keratosis Blennorrhagica (Reiter's Disease?) and Its Treatment. AMA Arch Derm. 1959;79(5):581–586. doi:10.1001/archderm.1959.01560170079012
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