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June 1959

Cat-Scratch Disease: A Selective Review

AMA Arch Derm. 1959;79(6):674-680. doi:10.1001/archderm.1959.01560180048014


In 1932, alert to the repeatedly recurring history of cat scratch in patients whose clinical diagnosis of tularemia could not be confirmed by specific agglutination, Lee Foshay, a microbiologist of Cincinnati, sorted out a group of cases and called them cat-scratch fever. Robert Debré, a French pediatrician, at about the same time was seeing, now and then, a case which was to prove to be this same ulceroglandular disease. The American and French investigators did not publish these observations, waiting to isolate the etiologic agent. In Greece, Petzetakis, in 1935, published a case of subacute monoadenitis he believed to be due to a lymphophilic virus and prepared and used antigen in its study.

In 1945, Dr. Franklin Hanger, in New York, had the disease himself, and he and Rose prepared autogenous antigen which Foshay and later Debré used on their patients, obtaining a positive intradermal re