It is about apodictic to say that one cannot speak of allergy without implying circulation, blood constituents, serology, serum constituents, agglutination, lysis, flocculation, the resources of defense that will isolate and destroy an offending protein; that these reactions may be local or generalized to a systemic level no one doubts; that these reactions may be so powerful that the defense goes far beyond the danger of the attack is well known in anaphylactic shock; that none of these reactions occurs without sensory stimulation, motor, and secretory nervous participation is also well known, whether these be at the spinal reflex level or by referred reactions.
The hub of the neuroses is the anxiety state. The acute anxiety state broadly takes one of two principal directions: (1) the anxiety state somatic expressed mainly by autonomic disturbances; (2) the anxiety state phobic manifested by panic reactions occasioned and attached
SIMONART PC. Allergy and Conditioning. AMA Arch Derm. 1959;79(6):700–704. doi:10.1001/archderm.1959.01560180074018
Customize your JAMA Network experience by selecting one or more topics from the list below.