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June 1959

Fusarium Oxysporum Infection of the Nail: Report of Cases

Author Affiliations

Galveston, Tex.

From the Department of Dermatology (J. Fred Mullins, M.D., Director), The University of Texas —Medical Branch.

AMA Arch Derm. 1959;79(6):705-708. doi:10.1001/archderm.1959.01560180079019

In the following two cases which clinically were diagnosed as fungus infection of the nail, Fusarium oxysporum was isolated. Both cases were of long standing and the use of a wide range of fungicides, and even removal of the nail in one case had been ineffective. In the following study results of sensitivity tests of F. oxysporum to various fungicides lead to cure in both cases.

Report of Cases

A 48-year-old white housewife, whose hobby was gardening, was seen in March, 1956, for a recurrent infection of the right thumbnail of five years' duration (Fig. 1). During this time her family physician had used a wide range of fungicides and had removed the nail twice. The entire nail plate was thin and flexible and undermined at the distal third, the nail bed being thickened and covered by dirty debris. Proximal to the undermined part, there was a half-moon-shaped, sharply

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