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June 1959

Erythema Multiforme (stevens-Johnson Syndrome) with Dermatitis Exfoliativa

Author Affiliations


From the Department of Dermatology, University of Cincinnati College of Medicine, and the Department of Internal Medicine, Jewish Hospital.

AMA Arch Derm. 1959;79(6):714-716. doi:10.1001/archderm.1959.01560180088022

There is continued interest (unfortunately, chiefly nosological) in the severe and extensive forms of erythema multiforme bullosum and in the response of these reactions to intensive corticosteroid therapy. We would like to report a case with skin involvement of the entire body. This is the severest form of this we have seen. We would agree with Friedmann and Pathé1 that severe ocular involvement and a serious prognosis are the essential characteristic features of this syndrome which distinguish this type from other forms of erythema multiforme bullosum. Since this term, Stevens-Johnson syndrome, is still used so commonly, we have employed this phrase. Dermatologists should prefer the term of severe erythema multiforme bullosum with ocular and mucosal involvement.

Report of Case

A 19-year-old white woman was admitted to the Jewish Hospital on June 8, 1958. This was her first episode of any skin, mouth, or eye trouble. Her illness

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