[Skip to Content]
[Skip to Content Landing]
Article
June 1959

THE HECHT TEST FOR DETECTING THE ANTIBODY IN SYPHILIS

Author Affiliations

Professor Emeritus of Immunology Western Reserve University School of Medicine Cleveland 6

AMA Arch Derm. 1959;79(6):722-723. doi:10.1001/archderm.1959.01560180096027

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.

Abstract

To the Editor:—On May 10, 1906, thus 53 years ago, an article entitled ``Eine Serodiagnostische Reaktion bei Syphilis" appeared in the Deutsche medizinische Wochenschrift. The method was introduced by Wassermann, Neisser, and Bruck and was based on the ingenious principles of Bordet and Gengou's complement fixation. It was an indirect method of detecting the antibody in syphilis, the direct methods dealing with the treponemata at that time having failed. The importance of this diagnostic aid in the discovery and control of syphilis can never be estimated.

The complications encountered in the performance of this complicated test led to numerous modifications, as well as to simplifications. In December, 1908, Dr. Hugo Hecht, then at Prague and now at Cleveland, published a preliminary paper under the title, "A Simplification of the Complement Fixation Test for Syphilis." This was followed within a few months by a second article. In May, 1910,

First Page Preview View Large
First page PDF preview
First page PDF preview
×