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June 1959


AMA Arch Derm. 1959;79(6):728-729. doi:10.1001/archderm.1959.01560180102031

Herpes Gestationis. Presented by Dr. Adrian Brodey.

A white woman aged 29 was first seen on July 18, 1955, for the treatment of a generalized bullous eruption which appeared one day postpartum. She had had toxemia of pregnancy with abruptio placenta and stillbirth. During labor she had received meperidine (Demerol), scopolamine, and phenobarbital (Luminal) sodium. Examination showed numerous generalized papulovesicular lesions and bullae. The impression was erythema multiforme bullosum due to medication. The patient improved with the administration of prednisolone. On Aug. 8 the white blood cell count was 38,550, with 60% eosinophils, but general physical examination by an internist excluded systemic disease. Subsequent blood cell counts showed a gradual restoration of the normal picture. The patient had to be maintained on reduced doses of corticosteroids until three months after onset. Two months later she had a mild recurrence following a

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