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August 1959

Onset of Psoriasis During the Course of Steroid Therapy

AMA Arch Derm. 1959;80(2):229. doi:10.1001/archderm.1959.01560200097019

In a recent publication Shelley and Harun1 reported that triamcinolone (9-α-fluoro-16-α-hydroxy-prednisolone) has been shown to have a significant temporary supressive effect on psoriasis. While Baer and Witten do not advocate the use of steroids as a routine treatment of psoriasis they did express the hope: ". . .with the development of newer analogues of cortisone it is entirely possible that this situation may change. For example triamcinolone appears to be more effective (in equivalent doses) in the management of psoriasis than the other corticosteroid drugs. Doses as small as 8 to 16 mg. daily may produce striking improvement in psoriasis vulgaris. . . ."2

We have a patient under observation who developed his first lesions of psoriasis while taking prednisone and triamcinolone for intractable asthma. Hence, it would indicate that these steroids could not even suppress the onset of psoriasis. To our knowledge no similar case has