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September 1959

Zirconium Granulomas of the Glabrous Skin Following Treatment of Rhus Dermatitis: Report of Two Cases

Author Affiliations

MC; (MC), U. S. A.

AMA Arch Derm. 1959;80(3):273-276. doi:10.1001/archderm.1959.01560210015003

Since the fall of 1956,1 granulomas of the axillae following the use of a stick type deodorant containing sodium zirconium lactate have been reported in increasing numbers. Their location has been invariably confined to the axillae, and they appear as reddish-brown discrete papules, 1 to 4 mm. in diameter. Shelley and Hurley2 have recently reviewed 64 cases previously reported and added 6 of their own. To date, there has been no evidence of skin reactions following the use of the insoluble hydrous zirconium oxide which has long been used in large quantities for treatment of Rhus dermatitis.3

The following report consists of two additional patients with zirconium granulomas, one of which occurred on the glabrous surfaces of both forearms and neck after repeated applications of hydrous zirconium oxide over an 18-month period.

Report of Cases

Case 1.—A 50-year-old Caucasian woman was treated

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