Leukoplakia—Leukokeratosis. Presented by Dr. Francesco Ronchese.
A white auto repairman, aged 65 years, has had lesions on his tongue for several years. He was hospitalized in 1946 for dizziness and ataxia, the diagnosis being encephalopathy due to carbon monoxide poisoning.
The patient shows white patches on the sides of the tongue and white, verrucous patches on top of the tongue of one year's duration.
After consultation at the Tumor Clinic of the Rhode Island Hospital, the consensus was that the patient had an epidermoid carcinoma of the tongue. Biopsy was recommended, with consideration of glossectomy if it proved confirmatory.
The blood Wassermann reaction was positive in 1955 and weakly positive in 1956. The microslide precipitation test was weakly reactive in 1958; Kolmer, reactive in 16 dilutions; Hinton, reactive in 1 dilution. Examination of the spinal fluid was normal. Biopsy showed no evidence of carcinoma.
NEW ENGLAND DERMATOLOGICAL SOCIETY. AMA Arch Derm. 1959;80(3):373–375. doi:10.1001/archderm.1959.01560210115025