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Article
September 1959

NEW YORK ACADEMY OF MEDICINE, SECTION OF DERMATOLOGY AND SYPHILOLOGY

AMA Arch Derm. 1959;80(3):376-377. doi:10.1001/archderm.1959.01560210118026
Abstract

Diagnosis: Chronic Bullous-Ulcerative Disease. Presented by Dr. Frank E. Cormia.

Discussion

Dr. Abraham J. Orfuss: In looking over the protocol I saw no indication that the λ-globulin determination was done.

Chairman Barker: The cryoglobulins were negative.

Dr. Orfuss: The λ-globulins.

Dr. Frank E. Cormia: She had a starch gel electrophoresis pattern, and the λ-globulins are normal.

Dr. David Bloom: In spite of a normal λ-globulin in the serum, I should suggest the diagnosis of pyoderma gangrenosum, which is very frequently associated with arthritis and not necessarily with ulcerative colitis. I believe that the patient will benefit by a strongly supportive therapy. Even λ-globulin injections may be of benefit in spite of a normal content in the serum.

Dr. Beatrice Kesten: I agree with Dr. Bloom that this belongs in the group of allergic vasculitis, namely, dermatitis nodularis necrotica. The psychogenic aspects are probably secondary. She has sinusitis and

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