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February 1960


Author Affiliations


AMA Arch Derm. 1960;81(2):266-278. doi:10.1001/archderm.1960.03730020102018

Dyskeratosis Congenita with Pigmentation, Dystrophic Unguis, and Leukokeratosis Oris. Presented by Dr. Ira Leo Schamberg.  Patient has suffered all his life from dysphagia. In May, 1959, a piece of meat got stuck in his throat, and esophagoscopy was carried out because of this in July. Two biopsies reported carcinoma of the lower cervical esophagus with ulceration and some narrowing. On x-ray examination the lesion was only 2 cm. in length. No leukokeratosis was observed in the esophagus. The patient has had no weight loss, has no evidence of metastasis, and is still (October, 1959) working. The lesion is under treatment with deep x-ray therapy.Protoscopic examination in September, 1959, revealed the mucous membrane to be unusually dry but no leukokeratosis was observed.

Congenital Ichthyosiform Erythroderma. Presented by Captain James H. Lockwood (MC), U.S.N.  The patient, a Caucasian, aged two and one-half years, born of normal pregnancy and delivery, at birth

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