Sarcoidosis with Unusual Hematologic Manifestation. Presented by Dr. Bernard Appel.
A woman, aged 64 years, American, has suffered from systemic symptoms for two and onehalf years, and an eruption on the upper part of her back and back of the neck for two months.In December, 1956, the patient noted palpitation and was treated with digitalis by her family physician. In February, 1957, symptoms of fatigue and "anemia" were treated by her doctor with injections of vitamin B12 without benefit. The fatigue became progressively worse, and she was admitted to the Lynn Hospital in July. The principal findings there were marked pallor, jaundice, and a spleen enlarged five fingerbreadths below the costal margin.The blood count showed red cells 9,100,000; white cells 10,000; hemoglobin 5.7 gm. per 100 cc., and reticulocytes 17%. The Coombs test was positive, 1:1024 (at 37 C, 4 C). The total bilirubin was 3.19 mg.
Goodman J, Hill WR. NEW ENGLAND DERMATOLOGICAL SOCIETY. AMA Arch Derm. 1960;81(2):304–307. doi:10.1001/archderm.1960.03730020140025
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: