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April 1960

Lichen Planus-like Eruptions Caused by a Color-Film Developer

Author Affiliations

New York

Associate Clinical Professor of Dermatology, New York Medical College; Assistant Attending Dermatologist, The Mount Sinai Hospital.

AMA Arch Derm. 1960;81(4):516-519. doi:10.1001/archderm.1960.03730040020004

Contact dermatitis following exposure to a chemical agent in color-film processing has been seen in eleven patients. In nine of the eleven cases, the skin eruptions clinically resembled lichen planus and in two cases the eruptions were erythematous and eczematous. Lichenoid eruptions from bacterial agents, spirochetes, fungi, and drugs have been described.1 Among the latter, penicillin, para-aminosalicylic acid, and the barbiturates are cited.2 The development of such lesions following skin contact with allergens is unusual.

Many of the color-forming developing agents have allergenic properties.3 Lichenoid eruptions from exposures to p-phenylenediamines among workers in a color photography processing plant were first described by Buckley,4 although the allergen was not identified.

All of the present series of cases were traceable to exposure to a single colordeveloping agent, CD2 (2-amino, 5-diethylaminotoluene monohydrochloride). CD2 was first used in the film processing plant in October, 1953, and the first patient

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