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April 1960

Xylocaine (Lidocaine) Viscous: A Topical Anesthetic Agent of Value for the Relief of Pain Associated with Oral Mucous Membrane Lesions

Author Affiliations

New York

From the Department of Dermatology and Syphilology of the New York University Post-Graduate Medical School (Dr. Marion B. Sulzberger, Chairman), and the Service of Dermatology and Syphilology of Bellevue Hospital (Dr. Morris Leider, Chief of Service).

AMA Arch Derm. 1960;81(4):609-610. doi:10.1001/archderm.1960.03730040113024

Painful lesions of the oral mucous membranes occur in a variety of conditions. Often such lesions represent mucous membrane manifestations of diseases that are more of the skin than of the mucous membranes per se. Pemphigus vulgaris and erythema multiforme are examples. In addition, there are painful lesions that are solely of the oral mucous membranes, like the canker sores of aphthous stomatitis. As much or more than any other specialist, the dermatologist is consulted for relief of conditions of the oral mucosa, and of the pain associated with them.

It is therefore important that the dermatologist be acquainted with agents that can alleviate the pain associated with mouth lesions. Xylocaine (lidocaine) Viscous 2% was studied for efficacy in this respect.

Materials and Methods  Xylocaine (lidocaine) Viscous 2% is a cherry-flavored, semisolid, gelatinous preparation of the following composition1:According to Sandler,2 the preparation "has low surface tension and

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