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May 1960

Effect of Griseofulvin on Tinea Capitis Caused by Microsporum Audouini

Author Affiliations

Ann Arbor, Mich.

From the University of Michigan Medical Center.

AMA Arch Derm. 1960;81(5):797-801. doi:10.1001/archderm.1960.03730050153027

Introduction  The curative effect of griseofulvin in tinea capitis caused by Microsporum audouini has been established by the few reports which have been published. Williams, Marten, and Sarkany1 were the first to report such a cure; Blank and Roth2 also included one patient with scalp infection caused by Microsporum audouini who was successfully treated with griseofulvin. Recently, a series of children with M. audouini infection of the scalp treated with griseofulvin has been reported from Washington, D.C.3 Tinea capitis caused by dermatophytes other than M. audouini has also been treated successfully by griseofulvin.2-6 The frequency, the anthropophilic aspect, and the resistance to all forms of therapy other than x-ray epilation make tinea capitis caused by M. audouini one of the most important of the dermatophyte infections. The present study was initiated to determine the optimum dosage and treatment schedule necessary to best manage tinea capitis produced

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