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May 1960

Griseofulvin Treatment at Saint Louis Hospital, Paris

AMA Arch Derm. 1960;81(5):806. doi:10.1001/archderm.1960.03730050162029

Since March, 1959, in the dermatology service of the St. Louis Hospital, Paris, 76 cases of tinea of the scalp were treated, with enough elapsed time to evaluate the results:

  1. Twenty-eight cases of favus (Trichophyton schoenleini), one of which was a generalized favus, were treated previously for 20 years without success.

  2. Sixteen cases of tinea were due to endothrix Trichophyton

    11 due to T. violaceum

    2 due to T. glabrum

    2 due to T. acuminatum

    1 due to T. soudanese

  3. Eleven cases of tinea were due to M. audouini.

  4. Twenty-one cases of tinea were due to M. canis.

The dose was 1 gm. a day, for 21 days. This dose was reduced since August, 1959, in T. schoenleini to 1 gm. for 3 days and 0.5 gm. for 18 days. In the beginning of the study, no local treatment was used. Afterwards, daily shampoos, rubbing with

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