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June 1960

Psoriasis in Association with SarcoidosisReport of a Case

AMA Arch Derm. 1960;81(6):983-986. doi:10.1001/archderm.1960.03730060099025

Psoriasis has been reported in association with a large number of cutaneous and systemic diseases, among which are lupus erythematosus,1 hyperthyroidism,2 scabies,3 lichen planus,4 syphilis,5 tuberculosis,6 adenoma sebaceum and neurofibromatosis,7 and acrodermatitis chronica atrophicans.8 It has been assumed that the relationship is coincidental.

A survey of the literature revealed no instance of psoriasis associated with sarcoidosis, and in view of this fact it was thought worth while to report the following case.

Report of a Case  Throughout the 15 years preceding her admission to the Mayo Clinic in 1958, a 45-year-old white woman has had lesions of psoriasis involving the knees, elbows, and scalp (Fig. 1). Her father had had psoriasis for many years; a brother had psoriasis at the most recent report.In 1948, the patient had noted the onset of an episodic dependent ankle edema which has continued to the present. Also, in 1948, she had first noted a mild shortness of breath, and her tolerance of exercise had decreased gradually from that time. Tachycardia had developed a year later and