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June 1960


Author Affiliations

Instituto Médico del Este Caracas, Venezuela.

AMA Arch Derm. 1960;81(6):989. doi:10.1001/archderm.1960.03730060105027

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To the Editor:—  From the study of pertinent literature it is apparent that no satisfactory therapeutic procedure is now available for ordinary cases of chromomycosis. Two small cases have been recently reported as cured after several infiltrations with solution of amphotericin B during relatively long periods of hospitalization.In my experience, satisfactory results can be attained along the following lines:

  1. Small lesions (susceptible of surgical excision without grafts) should be destroyed by resecting the whole skin, including a margin of apparently normal skin, 3-5 mm. wide.

  2. Lesions not amenable to the previous procedure should be irradiated once by administering a dose per field of 400 r at 80 kv without filter. Only periphery of the active borders and 1-2 cm. of the adjacent, apparently normal, skin should be irradiated. Remember that central parts of the active borders are mainly cicatricial.

A patient is discharged without further therapeutic measures.

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