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July 1960

Solitary Trichoepithelioma

Author Affiliations


From the Subdepartment of Dermatology, Department of Medicine, The Johns Hopkins Hospital and School of Medicine.

Arch Dermatol. 1960;82(1):35-40. doi:10.1001/archderm.1960.01580010041006

Solitary growths of the skin present a formidable diagnostic problem, usually finally resolved by microscopic examination of a biopsy specimen. Among such single lesions, trichoepithelioma is not well known. It is of particular interest, however, and the prebiopsy clinical impression is not too difficult to make, provided one thinks of this diagnostic possibility.

In this study, the term trichoepithelioma refers to a hamartomatous tumor of epithelial tissue differentiating toward hair structure. It does not at all refer to basalcell skin cancer with differentiation toward hair structure, nor in this essay is the term used to refer to secondary or acquired trichoepithelioma secondary to cystic processes.1

Trichoepithelioma is usually present clinically as a multiple disseminated process and is known as multiple benign cystic epithelioma or as epithelioma adenoides cysticum, names given for the same dermatosis by Fordyce2 and by Brooke,3 respectively, both in 1892. It consists clinically of

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