Diagnosis: Rothmund's Syndrome (Poikiloderma Congenitale of Thomson) vs. ?Pellagralike Changes. Presented by Dr. A. C. Curtis and Staff.
This Mexican child began to develop a strange atrophy of the skin beginning at about one year of age. He had been very ill from shortly after his birth until about 18 months of age, when he began to grow, eat, and develop fairly well. The atrophic disorder first appeared on the cheeks and external ears and then on the arms, buttocks, and, most recently, over the skin of his legs. There is no history of skin disease, developmental defects, or cataracts in the family, and no history of consanguinity. There are no untoward subjective symptoms. Physical examination was essentially normal except for the skin which showed extensive reticulated, pigmented, and atropic, though not telangiectatic, changes in the areas noted above. There were small islands of normal-appearing skin among the web-like pattern
Palmer AE, Grekin JN. DETROIT DERMATOLOGICAL SOCIETY. AMA Arch Derm. 1960;82(1):116–119. doi:10.1001/archderm.1960.01580010122028
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