In recent years there have appeared several reports of cases the principal clinical feature of which consisted of yellowish papules on the exposed areas of the skin.1-6 These lesions have appeared during childhood, or more often in adulthood, have slowly increased in number, and have sometimes been pruritic. A consistent feature has been their appearance in individuals much exposed to sunlight.
These cases have always been labelled "colloid milium'' or "colloid degeneration." The term "colloid," however, is admittedly poor and has been perpetuated only for lack of a better one. This group of reported cases has been a loosely bound one, since there existed no definitive staining reactions, there was a wide individual variation in clinical features, and also because there was no predictable response to treatment.
We feel, therefore, that the following case is a significant one because it is clinically striking and because it has been extensively
WOOLDRIDGE WE, FRERICHS JB. Amyloidosis: A New Clinical Type. Arch Dermatol. 1960;82(2):230–234. doi:10.1001/archderm.1960.01580020072011
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