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August 1960


Arch Dermatol. 1960;82(2):288-293. doi:10.1001/archderm.1960.01580020130041

Diagnosis: Bowen's Disease of the Penis: Response to Grenz Ray Therapy. Presented by Dr. Earle W. Brauer and Dr. S. Fried (by invitation).  A Negro man, aged 73, was first seen as a clinic patient in December, 1949, at which time he presented an ulcerated and indurated lesion on the penis of 8 months' duration. A biopsy specimen at that time showed no evidence of a malignancy. In April, 1957, a second biopsy specimen was read as ``psoriasiform dermatitis." Darkfield studies on the penile lesion were consistently negative, as were the serologic tests for syphilis. A search for Donovan bodies was fruitless. The Frei skin test was positive.The lesion failed to respond to various topical medicaments in addition to local and systemic antibiotic agents of every type.In May, 1958, a review of the previous biopsy specimens revealed evidence of intraepidermal epithelioma.Between June 5 and July 3, 1958,

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