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August 1960


Arch Dermatol. 1960;82(2):293-299. doi:10.1001/archderm.1960.01580020135043

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Premenstrual Purpura. Presented by Dr. Elizabeth F. Reed (by invitation) and Dr. Frederick Urbach.  The patient is a 31-year-old white woman. She complained of an eruption which had preceded, by three to five days, each menstrual period for about three years. The small red lesions would first appear on her lower extremities and then become bluish-purple, then brown, and disappear with the onset of her menses. No known aggravating factors, except possibly alcohol, which intensified her purpura. Her periods were normal in time and duration. She has no allergies.

Examination :  She is well developed and in good health. There are brownish discolorations over the lateral aspects of both legs, with spotted hyperpigmented discolorations of the dorsum of both feet. Pedal pulses palpable and no venous distention.

Laboratory Findings:  Remple-Leede test normal. Bleeding time 4 min. and 51 sec.; coagulation time 9 min.; platelet count 140,600 per cu. mm.; Hgb. 11.6

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