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September 1960

Degenerative Collagenous Plaques of the Hands

Author Affiliations

New Orleans

Markle Scholar in Medical Science (Dr. Clark).

From Division of Dermatology, Department of Medicine and the Department of Pathology, Tulane University School of Medicine, New Orleans, La.

Arch Dermatol. 1960;82(3):362-366. doi:10.1001/archderm.1960.01580030056007

This report describes the clinical and pathologic features of a series of patients we have observed with linear, firm plaques of the medial and lateral aspects of the hands. Five illustrative cases are presented. The lesions are bilateral and symmetrical and are situated at the juncture of the palmar and dorsal skin. Histologically, the process is characterized by a rather distinctive deposition of dense collagen and elastic tissue, involving most of the reticular dermis but usually sparing the papillary dermis and subcutis.

The condition is chronic, essentially asymptomatic, and slowly progressive. Our patients could not date the exact onset of their lesions but had noticed slow development over a 5- to 15-year period. The only symptom mentioned by any of the patients has been stiffness resulting from advanced involvement of the flexor creases. In the fully developed case, both hands are symmetrically involved. A firm plaque extends from near the

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