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To the Editor:
In an article published in June, 1959 (Psychologic Aspects of Allergy, A. M. A. Arch. Dermat. 79:685 [June] 1959) I stated that I had heard of no attempts to confirm or refute Charpy's 1953 claim that dinitrochlorbenzene sensitivity could be induced in the guinea pig's skin by application of the chemical to any part of the afferent nervous pathway up to and including the cerebral cortex.Dr. E. Lipman Cohen of London has kindly put me onto an appropriate reference. In a symposium volume entitled Le Mécanisme Physiopathologique de l'Eczéma, edited by Jacques Charpy and published by Masson in Paris in 1954, Prof. Guido Miescher states clearly on page 187 that he tried to reproduce this phenomenon and failed completely every time.
Harry L. Arnold. PSYCHOLOGIC ASPECTS OF ALLERGY. Arch Dermatol. 1960;82(3):428. doi:10.1001/archderm.1960.01580030122024