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September 1960


Arch Dermatol. 1960;82(3):437-441. doi:10.1001/archderm.1960.01580030131030

Granuloma Faciale Treated with Intradermal Dexamethasone (Deronil). Presented by Dr. Faye D. Arundell and Dr. Kenneth H. Burdick.  A 39-year-old white housewife was first seen in the Cleveland Clinic on April 1, 1959. She complained of two asymptomatic red spots on her face. The one on her right cheek had appeared during autumn of 1957. This had gradually increased in size and become darker in color. The lesion on the left cheek had appeared during the summer of 1958. Her general health had always been good.

Examination.—  A 1X4 cm. brownish-red, slightly elevated plaque with central telangiectasia was present on the right malar area. A similar 2X2 cm. plaque was present on the left cheek. The general examination revealed no abnormalities.

Biopsy.—  The biopsy from the right cheek shows a flattened epidermis. The dermis contains a patchy pleomorphic infiltrate composed of plasma cells, eosinophils, lymphocytes, histiocytes, and neutrophils. The infiltrate

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