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October 1960


Arch Dermatol. 1960;82(4):652-659. doi:10.1001/archderm.1960.01580040170037

Psoriasis of the Palms and Soles. Presented by Dr. Theodore Cornbleet and (by invitation) Dr. Richard Bernstein. 

Discussion  Dr. Stephen Rothman: In the first case presented fungi could not be demonstrated, and the tentative diagnosis of psoriasis of the nails was made. Still, "empirically," griseofulvin was ordered. I do not believe this drug ever should be given unless dermatophytae have been demonstrated in the lesions.Dr. Irene Neuhauser: I wish to agree with Dr. Rothman. The empirical use of griseofulvin is getting to be rather ridiculous. I think this practice reached its peak in a patient at County Hospital who was given griseofulvin for mycosis fungoides. Every day we see patients who have been given griseofulvin for all sorts of undiagnosed conditions. The organisms are fairly easily demonstrated in any mycotic infection and should be found before the drug is given.Dr. Stephen Rothman: If we hospitalize patients with palmar

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