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This, the first of three volumes collecting analytic methods of protein chemistry, concerns itself with separation and isolation procedures. It is divided into seven chapters as follows: Separation of Proteins, by S. Keller and R. J. Block; Isolation of Biologically Active Proteins, by K. Okunuki; Fractionation of Proteins by Adsorption and Ion Exchange, by S. Keller, R. J. Block, E. A. Peterson, and H. A. Sober; Fractionation and Characterization by Dialysis, by L. C. Craig; Partition by L. C. Craig; Multi-Membrane Electrodecantation by A. Polson and J. F. Largier, and Zonal Density Gradient Electrophoresis, by H. Svensson. The editors attempted to have techniques described in full, so that resort to the original literature would be unnecessary, but the goal may not have been completely attained. References listed are extensive. Much in the book by the same authors has appeared in other more ponderous and more expensive volumes, but this does