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November 1960

Results of Therapy of Localized Amyloidosis Using Derminjected Triamcinolone Suspension

Author Affiliations


Dermatology Service, Walter Reed General Hospital, Washington, D.C. (Col. Robert S. Higdon, MC, USA, Chief of Service).

Arch Dermatol. 1960;82(5):746-749. doi:10.1001/archderm.1960.01580050088012

A review of the standard dermatologic textbooks and recent literature failed to reveal any consistently effective therapy for localized amyloidosis (lichen amyloidosis). Because of this and the fact that the intense pruritus often associated with this condition is likely to persist unchecked, a course of intralesional steroid injections known to be effective in certain pruritic dermatoses was tried on a patient recently seen at this institution.

Report of a Case  A 43-year-old Latin-American male soldier was seen in the Dermatology Outpatient Clinic at Walter Reed General Hospital for the first time in July, 1959, for treatment of a chronic, pruritic dermatosis of the right pretibial and lateral calf regions. This dermatosis had begun as a dimesized patch of papules 5½ years earlier and had gradually spread to involve an area of approximately 10 by 17.5 cm. (Fig. 1).

Physical Examination.—  The physical examination was essentially negative except for the area

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