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November 1960

Localized Accidental Vaccinia

Author Affiliations

Charlottesville, Va.

From the Department of Dermatology, School of Medicine, University of Virginia, Charlottesville.

Assistant Resident in Dermatology (Dr. Weary), Professor of Dermatology (Dr. Wheeler), Lecturer in Dermatology (Dr. Lingamfelter), Department of Dermatology; Professor of Dermatology and Chairman of the Department of Dermatology (Dr. Cawley); School of Medicine, University of Virginia, Charlottesville.

Arch Dermatol. 1960;82(5):804-811. doi:10.1001/archderm.1960.01580050146022

One of the important consequences of accidental inoculation of the vaccinia virus into the skin, mucous membranes, or cornea is a localized regional infection, called localized accidental vaccinia. Localized accidental vaccinia occurring in unusual sites or modified in appearance by localization on mucous membranes may at times present a confusing clinical picture. The observation of several children with localized accidental vaccinia led to the present report which will be presented in the following order: (1) Report of Cases, (2) General Features of Localized Accidental Vaccinia, (3) Features of Localized Accidental Vaccinia Involving Special Sites, (4) Comment, (5) Summary.

Report of Cases 

Case 1.—  A Negro girl, age 5, was seen on Nov. 2, 1958, because of painful vulvar lesions and pain on urination. Symptoms were of three days' duration. The vulva was edematous and there were 12 painful lesions on the labia majora, labia minora, and posterior fourchet. The lesions, which